RESEARCH

The research activity is focused on the synthesis, characterization, and optimization of innovative compounds with potential pharmaceutical interest. Wet-lab and in silico approaches are combined to reach our goals. Concerning the wet-lab experimental work, this includes the synthesis, purification, and characterization of organic compounds of pharmaceutical interest but also the study of their metabolic stability and the safety risk assessment through metabolomics, lipidomics and high-content imaging analyses. Concerning the in silico approaches, they range from target identification, high-throughput virtual screening, drug repurposing, hit-to-lead optimization, physical-chemical and ADMET properties prediction, QSAR, and artificial intelligence.